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It acts on three key metabolic hormone receptors GIP, GLP-1, and glucagon (GCG) to help regulate appetite, insulin secretion, and energy balance
While tirzepatide demonstrates slightly greater weight loss efficacy, its side effect profile is similar to semaglutide, with gastrointestinal symptoms being most common
The National Institute of Diabetes and Digestive and Kidney Diseases, the Endocrine Society, and major obesity medicine organizations recognize GLP-1 receptor agonists as evidence-based interventions for obesity management in appropriately selected adult patients
About this article Cite this article Li, Y., Xue, K., Hu, R
doi: 10.1007/s12010-023-04501-1 184 WangYDingLWangRGuoYYangZYuLet al
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