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For pain management following TBI, the anti-inflammatory effects of these peptides provide secondary benefits beyond direct neuroprotection
At 10 mg/mL, doses above 10mg require more than 1.0 mL of liquid
5-Amino-1MQ targets the substrate binding site of NNMT the nicotinamide binding pocket competitively inhibiting nicotinamide methylation with an IC50 of 1.2 M under reference assay conditions
Only slight reversible creatinine decreases at very high doses (2 mg/kg) were noted
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