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For short-term or mild adverse events, dietary modifications are warranted and, for constipation, increased fiber/water intake can be recommended

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Lab Invest 96:839852 Schafer S, Viswanathan S, Widjaja AA, Lim WW, Moreno-Moral A, DeLaughter DM et al (2017) IL-11 is a crucial determinant of cardiovascular fibrosis

Albiglutide was somewhat less potent in receptor activation (its a large molecule, ~72 kDa), and required a larger dose (3050 mg weekly)