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We recommend 3-9 months of therapy initially to achieve full benefits
GSH also acts as a cytosolic predecessor of phytochelatins (PC), which are metal binders and catalyse the shuttle of metal ions and other xenobiotic that expedites the compound passage into the cell vacuole [81, 98]
If response is inadequate after the FDA-recommended evaluation period at therapeutic doses, consider switching to an alternative agent or referring for surgical revision evaluation in appropriate candidates
See warnings about CIPN increase
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