It has not received marketing authorisation from the MHRA, nor has it been evaluated or recommended by the National Institute for Health and Care Excellence (NICE)
Since the latter are thought to exert their glucose-lowering activity by preventing the degradation and inactivation (with regard to insulinotropic effects) of endogenously released intact, biologically active GLP-1 [9], their pharmacological action should critically depend on availability of the major substrate, GLP-1
Initially, GLP-1 medication was developed to treat type 2 diabetes and, although it is effective, other significant weight loss benefits were also found , leading to their use as a weight management tool
However, the extent of benefit varied substantially
Does oral BPC-157 work for gut health