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The key difference is dosing range
But there is still little clinical research in dogs, and the use in a veterinary practice is still regarded as an investigational/off-label use
Serious side effects are rare, occurring in less than 1 percent of users
It may be taken with or without food, at any time of day
The results show that an NO adduct on the sulfhydryl group effectively drives intermolecular disulfide bond formation in TTR, converting native protein into the dsNNTTR species, see Fig
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