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About 1 in 8 Americans uses GLP-1 drugs for diabetes, weight loss and other chronic conditions, including semaglutide (Ozempic, Wegovy) or tirzepatide (Mounjaro, Zepbound)

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However, a retrospective cohort study published in Diabetes Care did find that use of GLP-1 medications for 1-3 years was associated with a slightly increased risk of all thyroid cancer (adjusted hazard ratio 1.58) and medullary thyroid cancer specifically (adjusted hazard ratio 1.78)