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La logica gestionale la stessa della chirurgia bariatrica, dove la deprescrizione progressiva degli antiipertensivi parte attesa del percorso post-operatorio
The gut microbiota colonizes and reproduces on intestinal epithelial surfaces, secreting enzymes that catalyze carbohydrate and metabolize indigestible carbohydrates into gut metabolites, vitamins, and some neurochemicals (15)
For more on this topic, read JourneyLites article on GLP-1s vs
However, serious toxicity and even deaths have been reported [2, 6, 7]
As for the LEADER trial with liraglutide, the separation of cardiovascular events was later than that observed in studies of sodium-glucose co-transporter-2 (SGLT2) inhibitors, suggesting a different mechanism of benefit and one that might be related to slowing the progression of atherosclerosis
![Cardiovascular disease continuum-GLP-1 action. Adapted from [46]](https://www.researchgate.net/publication/357072789/figure/fig1/AS:1146405179654167@1650335702879/Cardiovascular-disease-continuum-GLP-1-action-Adapted-from-46.png)
