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One of the main obstacles of GBM treatment is the blood-brain barrier (BBB)
Users describe hunger that feels almost painful, not just increased appetite but genuine distress if food is not available
One phase two trial (mean age 58, with no upper age limit) demonstrated mean reduction in body weight of 15.6% in participants taking CagriSema, compared to 5.1% and 8.1% with semaglutide and cagrilintide in monotherapy, respectively, over 32 weeks
Accessed 29 July 2022
It's about restoring or amplifying what should already be happening which is why the side effect profiles of most therapeutic peptides are generally favorable, and why this category of treatment has attracted significant clinical research interest over the past decade
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