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6a), CREB-mediated transcription evoked mainly by L-VDCC/Ca 2+ /CaMKs appears to be involved in the activation of Bdnf transcription by GIN

In rats, the oral dose found to be effective was 10g/kg, or 1.6g/kg

Data analysis Unless stated otherwise, behavioral data and co-immunoprecipitation data were analyzed by two-way ANOVA with/without repeated measures using IBM SPSS Statistics 21 (IBM Corporation)

Any real effect would more plausibly be a triggered downstream cascade the peptide acting as a brief signal that sets something else in motion and the size of a trigger does not scale with effect the way a sedatives blood level does

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