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doi: 10.1016/j.tcb.2024.01.010 36 JiQ.ZhangL.YeH
Purification was performed by silica gel chromatography, with a yield of 67%
The mechanism of GLP-1-induced nausea involves central GLP-1R activation in the brainstem, specifically in the area postrema, which is the chemoreceptor trigger zone for vomiting
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