In a similar analysis of the Swedish National Diabetes Register, a decreasing trend in standardised incidence rates of diabetic nephropathy in people with type 1 diabetes was observed from 2001 to 2019, with no changes in the rates of ESKD over the same period [5]
That includes proactive management of side effects, candid conversations about the long-term nature of treatment, infrastructure to identify and support patients at risk of stopping and addressing the cost barriers that make GLP-1 therapy unsustainable for many. These measures are especially important, Al-Aly noted, because the cardiovascular protection provided by GLP-1 medication builds slowly, but it erodes quickly
others simply dont eat because theyre not hungry, so malnutrition can be an issue, says Leigh ODonnell, head of shopper and category insights at Kantar Retail IQ, which conducts ongoing shopper research on GLP-1 users
10.1073/pnas.2009680117 106 LopaschukG
KCl can be given in the same line with lipid and ammonia scavengers, weak recommendation, low quality evidence (2C)