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A review and analysis of trials of GLP-1 receptor agonists found that they reduce the risk of cardiovascular and all-cause mortality and stroke
104 GLP-1RAs have been shown to enhance endothelial cell function through anti-inflammatory and vasodilatory mechanisms
10.1016/j.neuro.2015.02.007 Neurotoxicology 156 WangY.OuyangM.GaoX.WangS.FuC.ZengJ.et al (2020)
This study aimed to critically assess the existing literature on the adverse effects of GLP-1 RAs to formulate appropriate risk-benefit prescription practices for their optimal utilization as metabolic disease therapeutics
Core molecular mechanisms encompass the targeted modification of inflammatory signaling molecules [408], oxidative alteration of pathogen entry-related proteins [204], and direct damage to host lipids/DNA [409]
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