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A meniscus tear is one of the most common causes of knee pain
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Chemotherapy with drugs like 5-fluorouracil has also been associated with acute thiamine deficiency by disrupting thiamine activation, so oncology patients receiving such therapy might receive parenteral thiamine supplementation as part of this B-Complex if needed
The copper ion is essential for biological activity the apo-peptide (GHK without copper) shows markedly reduced activity in most assay systems
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