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Retatrutide (research grade), also designated LY3437943, is a long-acting synthetic peptide engineered to co-engage three distinct G-protein-coupled receptors: the glucagon-like peptide-1 receptor (GLP-1R), the glucose-dependent insulinotropic polypeptide receptor (GIPR), and the glucagon receptor (GCGR)

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The LEAF findings suggest that preablation substrate stabilization using targeted medical therapy may improve longterm success better than empirically targeting AFib with additional ablation lesions

First, machine learning models need to improve