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Researchers first identified it decades ago and later discovered that levels tend to decline with age
Collagen peptides, when ingested, are broken down into smaller fragments that serve as both building blocks for new collagen synthesis and as signaling molecules that stimulate fibroblasts to produce more collagen
Additionally, the FOXO4-p53 interaction contributes to the maintenance of senescent cells by activating the transcription of their common target gene, p21cip1, which suppresses apoptosis 36
Hsu, and J.-H
Eighteen adult, female New Zealand white rabbits, all physically normal and weighing an average of 2.5 kg, were used
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