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NAFLD in the Elderly

The functions of amylin are complementary to insulin and to GLP-1 : Slows gastric emptying , similarly to GLP-1, but more strongly Suppresses glucagon , helps control postprandial glycemia Induces satiety , via the area postrema in the brainstem Regulates weight balance , long-term effect In type 2 diabetes amylin secretion deteriorates in parallel with insulin secretion , as the disease progresses, the -cells lose the ability to produce both hormones at once

Increased IGF-1 levels as a result of high GH may also increase the risk of developing certain types of cancer

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SELECT established Semaglutide as CV-protective therapy, CagriSema must demonstrate at least equivalent CV safety for broad clinical practice