The biological activity of GIP in adipocytes has been investigated for some time, and although there is a need for better understanding, GIP is implicated in adipocyte carbohydrate and lipid metabolism through regulation of glucose uptake [30], lipolysis [31], and lipoprotein lipase (LPL) activity [32]
So is there a reason to consider using GLP-1 analogs for effects other than weight loss or glucose control
33,34,35,36,37 One study suggests that length of time from diagnosis of cognitive impairment is important for response rate, in that patients who had experienced symptoms for less than 12 months improved on B12, whilst those with symptoms for more than 12 months continued to decline
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