While mild side effects can be normal, you should always contact your healthcare provider if you experience anything that feels severe or persistent
On the Columbia Suicide Severity Rating Scale (C-SSRS) during screening (within the last 28 days): A yes answer to question 4 (active suicidal ideation with some intent to act, without specific plan) on the suicidal ideation portion of the C-SSRS or A yes answer to question 5 (active suicidal ideation with specific plan and intent) on the suicidal ideation portion of the C-SSRS or A yes answer to any of the suicide-related behaviors (actual attempt, interrupted attempt, aborted attempt, preparatory act or behavior) on the suicidal behavior portion of the C-SSRS and the ideation or behavior occurred Prior or concomitant therapy
Once an oral small-molecule GLP-1 is approved, there may be an expectation that it will take over from the current peptides
Weeks 1-4: 2 mg per week (40 units) This is the adaptation phase
This process lowers blood sugar, reduces cravings, and slows digestion, helping you feel satiated for longer and preventing overeating