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Microglial cells in culture express a prominent glutathione system for the defense against reactive oxygen species

Mammalian Gpx1, GPx2 (this protein), Gpx3, and Gpx4 have been shown to be selenium-containing enzymes, whereas Gpx6 is a selenoprotein in humans with cysteine-containing homologues in rodents

Unlike stimulants such as phentermine, GLP-1s may aid in weight loss while also improving blood sugar control

In a 2026 trial, adults with alcohol use disorder and obesity taking semaglutide clocked in fewer heavy drinking days than those on placebo