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No dual or single agonist compound gives researchers access to the GCGR pathway
However, if the defenses are too weak, then infections cannot be handled or body cells can proliferate uncontrolled and grow to form tumors, which can become life threatening. In vivo, T-cell-specific ablation of murine Gclc prevented autoimmune disease but blocked antiviral defense, the Immunity article noted
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Y., Navakkode, S., Liu, F., Soong, T
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