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They also are sensitive to environmental conditions and can change chemical composition if stored at the wrong temperatures or shaken too vigorously, increasing the risk of an immune response or decreasing their effectiveness
This color change indicates that the oxygen in the trapped blood is being depleted
Clin Rev Allergy Immunol 42(1):515
As they are highly reactive, ROS can react with and damage important molecules, such as DNA , lipids (such as those in cell membranes) and proteins (including key enzymes and structural proteins)
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