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The major routes of elimination are biliary and fecal excretion, with a small fraction excreted in the urine
Natale P, Green SC, Tunnicliffe DJ, Pellegrino G, Toyama T, Strippoli GF
The peptide is being developed for topical application, and one additional benefit is that as a small protein, it will be safely broken down into naturally occurring amino acids after exerting its therapeutic effects
PP2A, the brains major phosphatase, is dysfunctional without methylation, allowing tau hyperphosphorylation to proceed unchecked
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