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This binding triggers a cascade of events inside the adipocyte (fat cell) that ultimately results in lipolysis - the breakdown of stored triglycerides into free fatty acids that can be burned for energy

One convergent pathway activated by IGF-1R and IR is the mTORC1 and mTORC2 signalling

The right dose depends on the indication, the patients weight and health history, and the prescribing providers clinical judgment

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