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A 2025 systematic review of 544 records found 35 preclinical and only 1 clinical study, and identified no clinical safety data

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Journal of Medicinal Chemistry, 64(17), 1118311194

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Defined stereoisomers of 2-amino NAD(+) and their activity against research subjects [PMID: 35716588] Laboratory literature summary: Defined stereoisomers of 2-amino NAD(+) and their activity against research subjects sirtuins and a bacterial (ADP-ribosyl) transferase