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It mimics glucagon-like peptide-1 (GLP-1), a hormone that targets brain areas involved in appetite regulation, helping patients feel fuller longer and consume fewer calories

Zepbound is also FDA approved for treating moderate-to-severe obstructive sleep apnea in adults with obesity

It represents the next generation of weight loss medications because it activates both GLP-1 and GIP receptors, a dual mechanism that clinical trials showed produces even greater weight loss than semaglutide alone

Patient has contraindication to sulfonylureas (history of hypoglycemia)

The exact implications of these findings require more research