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However, in a mouse model of inherited Purkinje cell degeneration, increased mitophagy and autophagy have been associated with Purkinje cell loss

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Continuous exposure to PTH, however, produces the opposite effect

In others, it appears that single piece IOL designs that integrate the haptic (which fixes the IOL into the capsular bag) with the optic do not create a robust seal between the optic and the lens capsule ( Figure 3B ) (84, 93, 94)

222 In breast cancer, NF1 loss drives resistance to PI3K inhibitors by activating RAS-MAPK signaling and promoting metabolic rewiring, including increased glycolysis and decreased ROS