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GLP-1RAs currently available on the market include semaglutide (sold as Ozempic and Rybelsus), liraglutide (Victoza), dulaglutide (Tulicity), exenatide ( Byetta and Bydureon ), and tirzepatide ( Mounjaro )

However, patient retention is a challengeabout 50% discontinue within a year due to cost, side effects, or goal achievement

We now have much better data on gallbladder risks thanks to major research studies in JAMA Internal Medicine

Here are the key administration guidelines: Choose injection sites with adequate fatty tissue: Abdomen (avoiding the belly button) Love handles Upper arm area Inner thigh region Always rotate injection sites to prevent tissue damage and maintain absorption efficiency