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Prior exposure to taxanes during treatment of mCRPC can induce resistance mechanisms, including upregulation of efflux pumps or mutations in tubulin, that may compromise the efficacy of microtubule inhibitor-based ADCs 246,247
Penicillamine, a copper chelator used in Wilson disease, requires dose adjustment in hepatic impairment precisely because liver function determines the rate at which mobilized copper can be processed and excreted [10]
Galarraga B, Ho M, Youssef HM, Hill A, McMahon H, Hall C, et al
In terms of opening the packet, it was very, very hard to open, but I guess that's a good thing as it shows the seal is secure
Additionally, I evaluated agronomic traits such as seed germination rate, efficiency, and seed size
