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For each cardiometabolic risk measure, three analyses were performed: estimation of the proportion of efficacy mediated by change from baseline in body weight, change from baseline in AHI and SASHB and, lastly, change from baseline in all three mediators combined

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Some patients transition to microdose protocols or alternative compounds if they experience tolerability concerns

These include both ones connected to high-street pharmacy chains or newer online firms that seem to have been set up solely to sell the weight-loss injections

Is dietary compliance consistent