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Retatrutide offers a "dual-defense" for the kidneys: Direct Effect: GLP-1 receptors in the kidneys reduce inflammation and oxidative stress in the delicate filtering units (nephrons)

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At the same time, more of your existing NAD+ gets consumed by enzymes like CD38 and PARPs, which are activated by things like inflammation, oxidative stress, and DNA damage

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In addition, a decrease in hypoxanthine and inosine has been observed in the plasma of PD patients, indicating a dysfunction in purine recycling

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