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Gut 2009;58:990-7.ArticlePubMed 49
Only 12.5% achieved 10% weight loss, while 22% gained at least 10%
Some patients taper off after reaching their goal and maintain results with lifestyle changes
Currently, the mainstay therapeutic agents for UC include 5-aminosalicylates, corticosteroids, immunomodulators and biologics, among which, biological agents, such as the tumor necrosis factor (TNF)- inhibitors, infliximab (IFX) and Golimumab (GLM) (8, 9), anti-47 integrin antibodies, vedolizumab (VDZ) (10) are the most classical and widely used medications for patients with UC, all of which can induce and maintain remission to promote mucosal healing (11)
