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The 2024 NICE guideline on B12 deficiency in over-16s is built around identifying and treating the cause, not just topping up the number
Oral Supplements: Generally take longer to show noticeable results, especially if absorption is compromised
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In addition, high levels of B12 and NAD have been correlated with longer telomeres, specialized proteins at the ends of linear chromosomes
However, for those with mild dietary deficiencies and intact absorption mechanisms, high-dose oral tablets can often be sufficient, albeit with potentially slower results
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