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10.1053/meta.2002.35193 150 SciaccaL.CassarinoM
Interestingly, in SURPASS-4, the overall cohort of tirzepatide users and those with 30 mg/g UACR experienced an acute dip in eGFR at 12 weeks, resembling the eGFR slope observed in trials with semaglutide and other nephroprotective drugs, such as RAAS blockers [50] and SGLT-2i [51]
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"If approved, retatrutide will be the first in a new class of medications." Eli Lilly announced results from its phase 3 trial TRIUMPH-4 in December, testing retatrutides effect on weight loss and other health conditions
The prescribing information for these medications contains a boxed warning regarding the potential risk of thyroid C-cell tumors, a rare form of thyroid cancer
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