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They can, indirectly

The fixed effects in the model included the treatment method, patients baseline lung function values, and follow-up visits (treated as categorical variables), and the random effects included the interaction of treatment with follow-up and center

Since GHK-Cu operates through different mechanisms (gene expression modulation, collagen synthesis, stem cell activation), non-responders to minoxidil may achieve results through this alternative pathway

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However, the extent to which these benefits are truly independent of weight loss may differ by condition, and more research is needed to clarify these relationships