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Side Effects: Gastrointestinal side effects, such as nausea, are common initially but can be managed by gradually adjusting the dosage
Many women also begin developing some level of insulin resistance or metabolic dysfunction during this phase of life, which makes weight management feel dramatically harder than it did in earlier decades
Given all these functions, identifying the mechanisms for energy balance in the CNS is important for understanding obesity as a disease and for developing effective pharmacotherapies for obesity
One such approach involves increasing the expression of EAATs to improve glutamate metabolism, thereby supporting neuronal survival
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