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While LipRSV reduced oxidative markers in the hippocampus, cerebellum and posterior cortex, the increase observed in the frontal cortex suggests that nanocarrier distribution and local redox balance may critically influence therapeutic outcomes

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Neutrophils, mononuclear phagocytes, and lymphocytes accumulate vitamin C to high concentrations, which can protect these cell types from oxidative damage

Regulatory standards cap levels of host-cell DNA/RNA and protein impurities to prevent immunogenic contaminations ( [44] )