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Large amounts of iron are found in the basal ganglia, substantia nigra, and cerebellum, likely reflecting the high metabolic demand and active neurotransmitter synthesis in these regions (Ghaderi et al
All included studies implemented linear MR analyses, and uncertainties exist in the ability to use MR in evaluating nonlinear effects (Reference Hamilton, Hughes and Lu116)
Though taking milk thistle the natural way may be better, it all boils down to your needs
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