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The successful patients arent always the easiest approvals
Therefore, these studies demonstrated that GLP-1RAs have an impact on preventing and stabilizing atherosclerotic vascular disease, which may translate into its protective effects against MACE in human subjects [59]
In the emulation of SURPASS-CVOT comparing tirzepatide to dulaglutide in patients at high cardiovascular risk (Table 2 and Supplementary Table 19), the estimated HR was 0.83 (95% CI 0.69 to 1.01) compared to the trial estimates of HR 0.92 (95% CI 0.83 to 1.01)
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