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People with higher starting body weight tend to lose a smaller percentage of their total weight compared to lighter individuals at the same dose, though they often lose more absolute pounds
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In this process, the renin-angiotensin-aldosterone system (RAAS) is assumed to play a role
Perhaps they are depressed
Additionally, case studies have shown that while GLP-1 medications can lead to weight loss, 40-60% of this loss might come from lean mass, which necessitates careful management to prevent muscle loss and maintain strength
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