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In conclusion, with isolated ECSCs, we found that hypoxia promotes the sustained stem-like state and that HIF-1 and HIF-2 activate the expression of ALKBH5, thereby increasing SOX2 levels by decreasing m 6 A levels through the demethylation of SOX2 mRNA
doi:10.3390/molecules1 91119066
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This imaging approach has been successfully used for the original roGFP2 probe and different roGFP1-iX variants (Wierer et al., Generally, roGFP probes are appropriate for measuring the thiol/disulfide equilibrium within a linear range of about 30 mV from their midpoint potential equivalent to an OxD between 10 and 90%