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doi: 10.1111/DOM.12824 50 LiuLShiHShiYWangAGuoNTaoHet al
Patients may experience severe nausea, dizziness, tachycardia, or mood instability
Peer reviewed
Key Takeaways Retatrutide is a once-weekly injectable triple agonist targeting GLP-1, GIP, and glucagon receptors Starting dose is typically 1 mg weekly, titrating up gradually to minimize side effects Maintenance doses range from 8 mg to 12 mg weekly based on individual response Titration is critical for balancing weight loss efficacy with tolerability Clinical trials show significant weight reduction compared to placebo Always work with a healthcare provider to determine your optimal dosing schedule Overview of Retatrutide What is Retatrutide
Common locations include the upper arm, abdomen, back, or thigh
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