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Description FOXO4-DRI is a D-retro-inverso peptide analogue derived from a FOXO4 interaction motif and used in non-clinical in vitro research involving proteinprotein interactions , cellular senescence pathways , and peptide structureactivity relationship studies

Its confidence interval spans zero and is wider than the point estimate, so it was too small to detect the difference it observed uninformative rather than null

The evidence is modest

Investigators have reported reductions in wrinkle depth, improvements in skin density, and increased dermal fibroblast activity in pre-clinical and limited human-skin studies [2][6]

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