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Thus, the overexpression of ABC2 contributed to EM resistance by serving as an efflux pump for chemotherapeutic agents [27]

These include: Complete Blood Count (CBC) to check for better anemia Serum Vitamin B12 levels to make sure the dose is right Methylmalonic acid (MMA) and homocysteine levels to see how the body is reacting Reticulocyte count to see how the bone marrow is doing Clinical Improvement Markers We also watch for signs of improvement in how patients feel

Common reported effects in clinical use include mild injection site reactions with subcutaneous administration, occasional digestive changes when taken orally, and rare reports of fatigue or dizziness

Usage: This product is intended strictly for laboratory research purposes and is not for human consumption

Workers exposed to plants containing parthenolide were thought to be susceptible to contact dermatitis, but current reports state that the drug is mutagenic in vivo and in vitro due to oxidative DNA damage or other possible mechanisms, raising concerns about the genotoxicity of the drug