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Incretin agents in type 2 diabetes
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El hallazgo estructural: activa cada receptor de forma distinta Un estudio de criomicroscopa electrnica y simulaciones de dinmica molecular revel una asimetra que explica buena parte de su farmacologa (PNAS, 2022 PMID 35333651): Sobre el GIPR , tirzepatida se comporta de forma muy parecida al GIP nativo
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