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A meta-analysis of 8 RCTs found that NAC supplementation significantly reduced fasting glucose (WMD: -5.84 mg/dL) and HbA1c (WMD: -0.27%) in people with metabolic conditions (Sarkaki et al., Clin Nutr ESPEN, 2021) [57]
Furthermore, it considers possible interventions, including dietary changes, pharmaceutical therapies, and surgeries, to relieve symptoms and improve patient's quality of life
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The mean weight loss in the semaglutide group was 13.6%, compared with 2.2% in the placebo group
Subcutaneous administration provides systemic delivery with rapid absorption and sustained antiinflammatory effects observed in daily dosing protocols [4]
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