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Researchers have developed dry powder inhalation systems and VIP conjugated with alpha-alumina nanoparticles (alpha-AN-VIP) that significantly reduced eosinophil counts, serum IgE, Th2 cytokines, and airway hyperresponsiveness in asthmatic animal models

This is due primarily to its twofold increase in fibroblast proliferation and vascular tissue growth

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Shaking can damage the peptide structure and reduce effectiveness