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Ezetimibe should be added if the goal is not achieved with the maximum tolerable dose of statin therapy
However, levels may be depleted by kidney and liver disease, genetic defects, valproic acid (an epilepsy drug), cancerand advancing age
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In the last 20 years, the emergence of pharmacological treatments for obesity based on gastrointestinal hormones has transformed the therapeutic landscape
The 0.25 mg dose is usually used as a starting dose, followed by an increase to 0.5 mg based on tolerance and clinical response
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