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Endometriosis is a chronic estrogen-dependent gynaecologic disease characterised by the presence of endometrial-like tissue outside the uterus, primarily on pelvic organs (e.g

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Furthermore, studies in Cryptococcus neoformans using thioredoxin reductase promoter replacement showed the enzyme's essential role in fungal cell viability, highlighting it as a potential antifungal target against this opportunistic pathogen (Missall and Lodge, 2005)