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[2] [4] Retatrutide is administered as a subcutaneous injection , typically once weekly, in a manner similar to other GLP-1-based therapies

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Though an elevated number of native LDL particles does not directly endanger endothelial cells, it does mean that there are more LDL particles available to become oxidized (or otherwise modified), which then become more likely to damage endothelial cells

Novo Nordisk stands behind the safety and efficacy of all its GLP-1 medicines when theyre used as indicated and taken under the care of a licensed health care professional, it says in a statement to TODAY.com